Title Utjecaj tjelesne aktivnosti na os mikrobiota crijeva mozak i mentalno zdravlje Title (english) The effect of physical activity on the microbiota gut brain axis and mental health Author Berta Mihić Mentor Marija Rakovac (mentor)Committee member Marija Rakovac (predsjednik povjerenstva)Committee member Tatjana Trošt Bobić (član povjerenstva)Committee member Renata Barić (član povjerenstva)Granter University of Zagreb Defense date and country 2023-05-24, Croatia Scientific / art field, SOCIAL SCIENCES Abstract Ljudski organizam može se smatrati složenim ekosustavom s velikom raznolikošću mikroorganizama koji žive unutar njega, a interakcije uspostavljene između mikroorganizama u gastrointestinalnom traktu i mozgu regulirane su središnjim i crijevnim živčanim sustavom. Sve više dokaza podupire važnost crijevne mikrobiote u reguliranju višestrukih funkcija povezanih s fizičkim i psihičkim zdravljem domaćina. Postoji mnogo čimbenika koji utječu na sastav crijevne mikrobiote, a među njima je i tjelesna aktivnost. Poznato je kako tjelesna aktivnost pozitivno utječe na ljudski organizam u cijelosti, a u ovom radu je detaljnije objašnjen utjecaj tjelesne aktivnosti na os mikrobiota-crijeva mozak i mentalno zdravlje. Mnoga istraživanja ukazuju na povezanost mikroflore crijeva, odnosno crijevnog (enteričkog) živčanog sustava s funkcijom središnjeg živčanog sustava. Kada se raznolikost crijevnih bakterija smanji dolazi do gastrointestinalnih i drugih poremećaja, među kojima su i psihički poremećaji, a taj put komunikacije poznat je kao os mikrobiota–crijeva–mozak. S obzirom da je utvrđeno da crijeva i mozak mogu komunicirati, pretpostavlja se da tjelesna aktivnost može ublažiti simptome različitih psihičkih poremećaja. Dakle, cilj ovog diplomskog rada je objasniti komunikacijski put osi mikrobiota-crijeva-mozak, na koji način tjelesna aktivnost utječe na mikrobiom i time dovodi do promjena u crijevima i mozgu te objasniti medijatorsku ulogu tjelesne aktivnosti u utjecaju osi mikrobiota-crijeva-mozak na mentalno zdravlje.
Abstract (english) The human organism can be considered a complex ecosystem with a great variety of microorganisms living within it and the interactions established between microorganisms in the gastrointestinal tract and the brain are regulated by the central nervous system and enteric nervous system. Increasing evidence supports the importance of gut microbiota in regulating multiple functions related to the host's physical and psychological health. There are many factors that influence the composition of the intestinal microbiota, and physical activity is among them. It is known that physical activity has a positive effect on the human body, and in this thesis, the impact of physical activity on the microbiota-gut brain axis and mental health is explained in more detail. Many studies have pointed to the great connection and importance of the gut microflora, i.e. the intestinal nervous system and the function of the central nervous system. When the diversity of intestinal bacteria decreases, gastrointestinal and other disorders occur, including psychological disorders, and this communication pathway is known as the microbiota-gut-brain axis. Since it has been established that the gut and the brain can communicate, it is assumed that physical activity can alleviate the symptoms of various psychological disorders. Therefore, the goal of this thesis is to explain the communication path of the microbiota-gut-brain axis, how physical activity affects the microbiome and thus leads to changes in the gut and brain, and to explain the mediating role of physical activity in the influence of the microbiota-gut-brain axis on mental health.
Keywords
crijevni mikrobiom
središnji živčani sustav
crijevni živčani sustav
komunikacijski put
psihički poremećaji
Keywords (english)
gut microbiome
central nervous system
enteric nervous system
communication pathway
psychological disorders
Language croatian URN:NBN urn:nbn:hr:117:054815 Study programme Title: Kinesiology; specializations in: Kinesiology in Education and Track-and-Field, Kinesiology in Education and Fitness, Kinesiology in Education and Wrestling, Kinesiology in Education and Sailing, Kinesiology in Education and Windsurfing, Kinesiology in Education and Judo, Kinesiology in Education and Kayaking, Kinesiology in Education and Kinesiological Recreation, Kinesiology in Education and Kinesitherapy, Kinesiology in Education and Physical Conditioning of Athletes, Kinesiology in Education and Basketball, Kinesiology in Education and Football, Kinesiology in Education and Volleyball, Kinesiology in Education and Basic Kinesiological Transformations, Kinesiology in Education and Dancing, Kinesiology in Education and Swimming, Kinesiology in Education and Rhythmic Gymnastics, Kinesiology in Education and Handball, Kinesiology in Education and Skiing, Kinesiology in Education and Artistic Gymnastics, Kinesiology in Education and Management of Sport, Kinesiology in Education and Tennis, Kinesiology in Education and Rowing Type of resource Text File origin Born digital Access conditions Open access Terms of use Created on 2023-06-21 08:45:11
